Ingredient Encyclopedia

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Ingredient Encyclopedia

Kojic Acid – Benefits, Side Effects & Uses

by ThankMeNow Editors on Sep 10, 2025
Kojic Acid ($C_{6}H_{6}O_{4}$) is a natural metabolite produced by several species of fungi, particularly Aspergillus oryzae (the same mold used in sake fermentation). In dermatology, it is classified as a potent tyrosinase inhibitor. Unlike AHAs that physically peel the skin, Kojic Acid works chemically by chelation—it binds to the copper ions required by tyrosinase (the enzyme responsible for melanin production). By "locking up" these copper ions, Kojic Acid prevents the enzyme from converting the amino acid tyrosine into pigment. Because it is highly potent even at low concentrations, it is valued for its ability to target the "root" of a dark spot without requiring aggressive surface exfoliation.