Ingredient Encyclopedia

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Discover what’s inside your skincare — from retinol to aloe vera — with clear guides on benefits, uses, and safety.

Ingredient Encyclopedia

Panthenol (Pro-Vitamin B5) – Benefits, Side Effects & Uses

by ThankMeNow Editors on Sep 10, 2025
Panthenol (1$C_{9}H_{19}NO_{4}$) is the alcohol analog of pantothenic acid (Vitamin B5).2 In biochemistry, it is known as a precursor to Coenzyme A, which is vital for cellular metabolism and the synthesis of fatty acids.3 When applied topically, it is uniquely penetrative; it doesn't just sit on the surface like some humectants but travels deep into the stratum corneum.4 Once absorbed, it converts into pantothenic acid, which stimulates fibroblast proliferation—the process that builds new skin tissue.5 Because it is both a humectant (drawing water in) and an emollient (smoothing the surface), it acts as the "cellular cement" that fills in the cracks of a damaged skin barrier, making it indispensable for rapid recovery.