Ingredient Encyclopedia

Alpha arbutin is a gentle, effective skin-brightening ingredient that targets dark spots, hyperpigmentation, and uneven tone. It is widely used in serums and treatments for sun spots, post-acne marks, and age-related discoloration. What is Alpha Arbutin? Alpha arbutin is a naturally derived compound that inhibits melanin production, helping to reduce the appearance of dark spots and hyperpigmentation over time. Unlike harsh brightening acids, it is generally well-tolerated by most skin types, making it suitable for sensitive skin when introduced gradually. Key Benefits Reduces hyperpigmentation: Helps fade sun spots, post-acne marks, and uneven tone. Gentle brightening: Less irritating than hydroquinone or strong acids. Supports even skin tone: Promotes a radiant, balanced complexion. Who Should Use It? Individuals targeting sun spots, melasma, or post-inflammatory hyperpigmentation. Those seeking gentle brightening without irritation. All skin types, including sensitive skin (with gradual introduction). Who Should Avoid It? Those with extremely reactive skin may need patch testing first. Avoid combining with too many strong actives initially. How to Use It in a Routine Apply AM or PM after cleansing and toning, before moisturiser. Consistency is key: daily use produces best results. Always pair with SPF 30+ in the morning to protect skin and prevent new pigmentation. Can be safely combined with niacinamide, hyaluronic acid, or peptides. Verdict Alpha arbutin is a gentle, effective brightening ingredient. Consistent use paired with SPF leads to gradual improvement in dark spots and even tone. 👉 Try our Brightening Spot Serum for a beginner-friendly introduction to Alpha Arbutin. FAQs Is Alpha Arbutin safe for sensitive skin?Generally well-tolerated. Patch test if unsure or if you are using other actives. Can I combine Alpha Arbutin with other actives?Yes, it pairs safely with niacinamide, hyaluronic acid, or mild AHAs. Avoid layering with multiple strong acids initially. How long until I see results?Visible improvements in dark spots typically appear after 4–8 weeks of consistent use, alongside daily SPF protection. Related: Niacinamide Guide · Retinol Guide · Hyaluronic Acid Guide References PubMed: Alpha Arbutin – Skin Brightening Study Healthline: Alpha Arbutin Benefits and Uses American Academy of Dermatology – Brightening Ingredients Written by: Sarah Mitchell, Skincare Writer & Brand Educator Reviewed by: Dr. Priya Kaur, Consultant Dermatologist

Mandelic acid is a gentle alpha hydroxy acid (AHA) derived from bitter almonds. Its larger molecular size makes it slower to penetrate the skin, which reduces irritation compared to glycolic acid while still promoting exfoliation and brighter, more even skin tone. This guide explains what mandelic acid does, who it suits, how to use it safely, and potential side effects. What is Mandelic Acid? Mandelic acid is an AHA that helps loosen the bonds between dead skin cells, encouraging gentle exfoliation. Because of its larger molecule, it penetrates more slowly and is less likely to cause stinging or redness, making it suitable for sensitive or reactive skin types. It can improve overall skin texture, reduce pigmentation irregularities, and support product absorption. Key Benefits Gentle Resurfacing: Smooths uneven texture without harsh irritation. Improves Skin Tone: Reduces appearance of hyperpigmentation and dark spots over time. Less Stinging than Glycolic: Ideal for beginners or sensitive skin types. Supports Cell Turnover: Encourages healthy, radiant skin over weeks of use. Can Help Reduce Blemishes: Mild antibacterial properties may assist acne-prone skin. Who Should Use It? Sensitive skin types looking for a mild exfoliant. Individuals with darker skin tones seeking gentle brightening without irritation. Beginners who want to introduce chemical exfoliation gradually. Who Should Avoid It? Those currently overusing other strong actives such as retinoids, benzoyl peroxide, or other AHAs/BHAs. People with compromised skin barriers, eczema flare-ups, or open wounds. Those allergic to almonds or mandelic acid (rare). How to Use It in a Routine Use at night 1–3 times per week, depending on tolerance. Apply after cleansing and before serums or moisturisers. Follow with a nourishing moisturiser to maintain barrier integrity. Always wear SPF 30+ the following day, as AHAs increase sun sensitivity. Concentration & Formulation Most over-the-counter mandelic acid serums contain 5–10% concentrations, suitable for home use. Professional treatments can reach higher concentrations (20–40%) and should be done under dermatological supervision. Formulations may also include soothing ingredients like hyaluronic acid, aloe vera, or niacinamide to reduce irritation. Possible Side Effects Mild tingling or redness immediately after application (normal and temporary). Dryness or slight peeling if overused or layered with multiple actives. Increased sensitivity to sunlight; SPF is essential during daytime. Verdict Mandelic acid is a beginner-friendly AHA that gently exfoliates while improving tone and texture. Ideal for sensitive and darker skin types, it provides noticeable results with minimal irritation when used consistently. 👉 Ready to try mandelic acid? Discover our Mandelic Resurfacing Serum — a gentle yet effective serum for smooth, radiant skin. FAQs Is Mandelic Acid safe for sensitive skin?Yes, its larger molecule makes it gentler than many AHAs. Start slowly and moisturise afterward. Can I combine Mandelic Acid with other actives?Yes, but avoid layering with strong acids or prescription retinoids in the same routine. Consider alternating nights for best results. How long until I see results?Many users notice smoother skin within a week, with improved tone and radiance after 4–6 weeks of consistent use. Related: Lactic Acid Guide · Glycolic Acid Guide · Niacinamide Guide References PubMed: Mandelic Acid in Dermatology American Academy of Dermatology – AHAs Explained Healthline: Mandelic Acid Benefits for Skin Written by: Sarah Mitchell, Skincare Writer & Brand Educator Reviewed by: Dr. Priya Kaur, Consultant Dermatologist

Lactic acid is a gentle alpha hydroxy acid (AHA) that not only exfoliates dead skin cells but also helps boost hydration. It is one of the most beginner-friendly exfoliating acids, making it a great option for those with dry, sensitive, or mature skin. This guide explains what lactic acid does, who it suits, how to use it correctly, and what to watch out for. What is Lactic Acid? Lactic acid is a naturally occurring AHA derived from milk (though most modern formulations are vegan and lab-synthesised). It works by loosening the bonds between dead skin cells, allowing them to shed more easily. This leads to smoother, more radiant skin and improved product absorption. Unlike glycolic acid, lactic acid is slightly larger in molecular size, meaning it penetrates more slowly and is less irritating — perfect for beginners. Key Benefits Gentle Exfoliation: Provides a mild resurfacing effect suitable for most skin types. Hydrating Effect: Lactic acid is a humectant, meaning it attracts moisture and helps keep the skin plump. Smoother Texture: Softens rough patches and improves overall skin feel. Brighter Complexion: Promotes a more even, radiant skin tone over time. Supports Collagen Production: Regular use can help reduce the appearance of fine lines and improve firmness. Who Should Use It? People with dry or dehydrated skin who want mild exfoliation without irritation. Those new to chemical exfoliation and looking for a starter acid. Mature skin types seeking gentle cell turnover to improve radiance. Who Should Avoid It? Individuals with a damaged or compromised skin barrier (eczema flare, open wounds, or infection). Those using strong retinoids, benzoyl peroxide, or other potent exfoliants daily — over-exfoliation may lead to redness and irritation. Anyone allergic to lactic acid (rare — patch testing recommended). How to Use It in a Routine Frequency: Start 1–2x per week in the evening, then increase to 3x per week if tolerated. Application Order: Use after cleansing and before serums/moisturisers. Follow with Moisturiser: Helps lock in hydration and maintain barrier function. SPF Daily: As with all AHAs, lactic acid increases sun sensitivity, so a broad-spectrum SPF 30+ is essential during the day. Concentration & Product Types Most over-the-counter lactic acid products range between 5–10% concentration, which is considered safe for regular home use. Professional peels may use higher concentrations (20–50%) and should be performed under dermatological supervision. Possible Side Effects Mild tingling or redness after application (normal and usually temporary). Peeling or dryness if used too frequently or layered with too many actives. Sun sensitivity — always pair with SPF. Verdict Lactic acid is an excellent choice for beginners or those with dry, sensitive, or mature skin who want gentle exfoliation and a hydration boost. When used correctly, it helps reveal smoother, brighter, more supple skin. 👉 Ready to try lactic acid? Discover our Lactic Glow Serum — a beginner-friendly formula designed for gentle exfoliation and hydration. FAQs Is Lactic Acid safe for sensitive skin?Yes, lactic acid is considered one of the mildest AHAs. Start slowly and always moisturise afterward. Can I combine Lactic Acid with other actives?Yes, but avoid layering with strong acids, physical scrubs, or prescription-strength retinoids in the same routine. Consider alternating nights. How long until I see results?Many users notice softer, smoother skin within a week, with more visible brightness and tone improvement after 4–6 weeks of consistent use. Related: Glycolic Acid Guide · Niacinamide Guide · Hyaluronic Acid Guide References PubMed: Role of Lactic Acid in Skin Physiology American Academy of Dermatology – AHAs Explained Healthline: Lactic Acid Benefits for Skin Written by: Sarah Mitchell, Skincare Writer & Brand Educator Reviewed by: Dr. Priya Kaur, Consultant Dermatologist

Reviewed by Thank Me Now Skincare Editor · Last updated: September 2025 Salicylic Acid is one of the most popular beta hydroxy acids (BHAs) in skincare. Known for its ability to unclog pores and calm inflammation, it's a favourite among dermatologists for treating blackheads, whiteheads, and breakouts. What is Salicylic Acid? Salicylic acid is an oil-soluble exfoliant that penetrates deep into pores, breaking down the mix of dead skin cells and sebum that cause congestion. It has anti-inflammatory properties, making it particularly helpful for acne-prone and oily skin types. Key Benefits Decongests and clears clogged pores (PMC) Reduces blackheads, whiteheads, and visible blemishes Helps control excess oil production Calms redness and inflammation Smooths skin texture over time Who Should Use It? Oily or combination skin Acne-prone skin with persistent blackheads Congested T-zone areas Who Should Avoid It? Very dry or sensitised skin (may worsen dryness) People allergic to aspirin (salicylic acid is related) Pregnant individuals should consult their doctor before use How to Use It in a Routine Use 2–4x/week after cleansing as a toner, serum, or treatment Introduce gradually to avoid irritation Always follow with a hydrating moisturiser Daily SPF is essential — salicylic acid increases sun sensitivity Verdict Salicylic acid is a gold-standard pore-clearing ingredient. With consistent use, it helps prevent breakouts, smooths skin, and keeps congestion under control. 👉 Struggling with clogged pores? Try our BHA Pore Refiner — formulated to gently exfoliate and minimise breakouts. FAQs Can I use Salicylic Acid every day?Yes, some people can tolerate daily use. Start with 2–3 times per week and increase as your skin adjusts. Can I combine Salicylic Acid with Retinol?Yes, but introduce them on alternate nights to reduce irritation risk. How long until I see results?Blackheads and breakouts often improve within 4–6 weeks of consistent use. References Kligman D. “Topical Salicylic Acid in Acne Management.” Clin Cosmet Investig Dermatol. 2017. DermNet NZ: Salicylic Acid Overview NHS: Salicylic Acid – Uses and Safety Information About the Author: This article was reviewed by the Thank Me Now Skincare Editorial Team, combining science-backed research and real-world skincare experience to help you build a clear, effective routine. Related Guides Salicylic Acid vs Benzoyl Peroxide – For Breakouts How to Layer Acids Without Irritation A Complete Guide to Exfoliating Acids

Glycolic acid is one of the most popular alpha hydroxy acids (AHAs) used in skincare. Known for its ability to exfoliate the skin’s surface, glycolic acid helps to reveal smoother texture, boost radiance, and fade uneven pigmentation. This guide explains what glycolic acid does, who it suits, possible side effects, and how to safely add it to your skincare routine. What is Glycolic Acid? Glycolic acid is a water-soluble AHA derived from sugarcane. It has the smallest molecular size of all AHAs, which means it penetrates the skin effectively. It works by loosening the bonds (desmosomes) between dead skin cells, allowing them to shed more easily. This promotes cell turnover, resulting in a fresher, more even-looking complexion. Key Benefits Exfoliates Gently: Removes dull, dead skin cells for a smoother surface. Brightens Skin: Promotes a more radiant, even-toned complexion. Fades Dark Spots: Helps reduce the appearance of hyperpigmentation and post-acne marks over time. Improves Texture: Smooths rough or uneven skin and softens fine lines. Boosts Absorption: Allows serums and moisturisers to penetrate more effectively. Who Should Use It? People with dull, rough, or congested skin looking for a glow boost. Those with uneven tone or dark spots seeking a more even complexion. Normal, oily, and combination skin types typically tolerate glycolic acid well. Who Should Avoid It? Those with very sensitive, rosacea-prone, or compromised skin barrier (consult a dermatologist first). People using multiple strong actives (like prescription retinoids) — use with caution to avoid irritation. Avoid during periods of intense sun exposure if SPF is not used consistently. How to Use It in a Routine Frequency: Start 1–2x per week at night, build up to 3x weekly as tolerated. Application Order: Use after cleansing and before serums or moisturisers. Moisturise: Always follow with a hydrating moisturiser to protect the skin barrier. Sun Protection: Use SPF 30+ daily — glycolic acid increases sun sensitivity. Concentration & Product Types Over-the-counter glycolic acid products typically range from 5–10% concentration, which are suitable for most skin types. Higher percentages (20–70%) are reserved for in-clinic chemical peels and should only be performed by trained professionals. Possible Side Effects Temporary redness or tingling after application. Dryness or peeling if overused or used with other exfoliants. Increased sun sensitivity — SPF is non-negotiable when using AHAs. Verdict Glycolic acid is one of the most effective ingredients for smoother, brighter, and more even-toned skin — but it should be introduced gradually and paired with moisturiser and SPF to avoid irritation. 👉 Looking for a beginner-friendly option? Try our Glow AHA Exfoliant for a gentle yet effective boost to your routine. FAQs Is Glycolic Acid safe for sensitive skin?It can be, if used at a lower concentration and less frequently. Always patch test and introduce slowly. Can I combine Glycolic Acid with other actives?Yes, but avoid layering with strong retinoids, scrubs, or other AHAs/BHAs in the same routine to minimise irritation. How long until I see results?Visible improvement in brightness and texture can be seen within a few weeks of consistent use. Related: Salicylic Acid Guide · Niacinamide Guide · Hyaluronic Acid Guide References PubMed: Glycolic Acid in Dermatology American Academy of Dermatology – Alpha Hydroxy Acids Healthline: Glycolic Acid Overview Written by: Sarah Mitchell, Skincare Writer & Brand Educator Reviewed by: Dr. Priya Kaur, Consultant Dermatologist

Azelaic acid is a gentle yet effective multitasker that helps calm redness, manage breakouts, and even skin tone. It is well-tolerated by most skin types, including sensitive and rosacea-prone skin. This guide explains what azelaic acid does, who it suits, how to use it safely, and potential side effects. What is Azelaic Acid? Azelaic acid is a naturally occurring dicarboxylic acid found in grains such as wheat, barley, and rye. Topically, it works to normalize keratin production, reduce inflammation, target acne-causing bacteria, and fade hyperpigmentation. Its gentle nature makes it a versatile option for a variety of skin concerns. Key Benefits Calms Redness: Reduces irritation and is suitable for rosacea-prone skin. Helps with Blemishes: Mild antibacterial properties assist acne-prone skin. Evens Skin Tone: Targets dark spots and post-inflammatory hyperpigmentation. Gentle Compared with Many Actives: Lower irritation risk than strong AHAs/BHAs or retinoids. Supports Barrier Health: Non-stripping, so it can be used with other gentle actives. Who Should Use It? Individuals with redness, rosacea-prone skin, or sensitive skin. Acne-prone skin types seeking gentle blemish control. Those targeting hyperpigmentation or uneven skin tone. Who Should Avoid It? People with extremely sensitive or compromised skin may need slow introduction. Patch test recommended if using multiple actives simultaneously. How to Use It in a Routine Use AM or PM after cleansing, before moisturisers. Layering is safe with niacinamide, hyaluronic acid, or ceramides. Start with a lower concentration (10–15%) and increase as tolerated. SPF 30+ recommended if used in the morning. Verdict Azelaic acid is a well-tolerated, versatile active for calming redness, managing breakouts, and improving tone. Ideal for sensitive and acne-prone skin types. 👉 Ready to try azelaic acid? Explore our Calming Clarifying Cream for gentle, effective results. FAQs Is Azelaic Acid safe for sensitive skin?Yes, it is generally well tolerated. Introduce gradually and patch test if needed. Can I combine Azelaic Acid with other actives?Yes, it pairs well with gentle serums such as niacinamide or hyaluronic acid. Avoid over-exfoliation with strong acids in the same routine. How long until I see results?Visible improvements in redness and tone typically appear after 4–8 weeks of consistent use. Related: Niacinamide Guide · Retinol Guide · Hyaluronic Acid Guide References PubMed: Azelaic Acid in Dermatology American Academy of Dermatology – Azelaic Acid Overview Healthline: Azelaic Acid Benefits for Skin Written by: Sarah Mitchell, Skincare Writer & Brand Educator Reviewed by: Dr. Priya Kaur, Consultant Dermatologist

Vitamin C is a brightening antioxidant that supports collagen production and helps protect skin from environmental stressors such as UV damage and pollution (PubMed). What is Vitamin C? Vitamin C (ascorbic acid) is a water-soluble antioxidant naturally found in the skin. Topical application can help reduce free radical damage, support collagen synthesis, and improve skin tone (DermNet NZ). Key Benefits Brightens and evens tone (PubMed) Supports collagen signalling for firmer skin Protects against free radical and environmental damage Helps fade dark spots and hyperpigmentation over time Who Should Use It? Dull or uneven skin tone Hyperpigmentation concerns Normal to oily skin types (L-ascorbic acid preferred) Who Should Avoid It? Very sensitive skin (consider derivatives like magnesium ascorbyl phosphate) Those irritated by low pH formulas How to Use It in a Routine Apply in the morning before moisturizer and sunscreen (PubMed) Pairs well with SPF to enhance photoprotection Avoid layering directly with strong exfoliants to reduce irritation Verdict Vitamin C is a powerful daytime antioxidant. Start with lower concentrations if you have sensitive skin, or switch to gentler derivatives. Consistent use with SPF yields the best results. 👉 Looking for a beginner-friendly option? Try our Nature’s Vitamin C – Lemon, Orange & Tangerine Seed Facial Oil 30ml. FAQs Is Vitamin C safe for sensitive skin?Many find it tolerable; patch test if unsure (DermNet NZ). Can I combine Vitamin C with other actives?Yes, often with pacing. Avoid over-exfoliation to reduce irritation. How long until I see results?Typically 4–8 weeks of consistent use; always protect with SPF (PubMed). Related: Niacinamide Guide · Retinol Guide · Hyaluronic Acid Guide Related Guides Can You Use Vitamin C and Sunscreen Together? How to Store Vitamin C Serum Niacinamide vs Vitamin C – Can You Use Them Together? Vitamin C vs Ferulic Acid – Do You Need Both? Vitamin C vs Retinol – Morning Brightening or Night Renewal? References Pullar JM, Carr AC, Vissers MCM. "The Roles of Vitamin C in Skin Health." Nutrients, 2017. PMID: 28786984. DermNet NZ – Vitamin C in Skincare Telang PS. "Vitamin C in dermatology." Indian Dermatol Online J, 2013. PMID: 24049774.

Hyaluronic Acid (HA) is a naturally occurring molecule in the skin that binds and retains water, helping keep skin plump, smooth, and hydrated. It can improve skin elasticity, reduce fine lines, and enhance overall skin comfort (PubMed). What is Hyaluronic Acid? HA is a glycosaminoglycan found in connective tissue. Topical HA attracts water to the skin surface, supporting hydration and barrier function. Its soothing properties make it suitable for nearly all skin types (DermNet NZ). Key Benefits Immediate Hydration – Attracts and holds water, reducing dryness (PubMed) Plumper, Smoother Skin – Softens fine lines and wrinkles (PMC) Enhances Tolerance of Other Actives – Reduces irritation from retinoids and acids Supports Skin Barrier – Helps maintain moisture and resilience (DermNet NZ) Universal Compatibility – Suitable for sensitive, dry, or acne-prone skin Who Should Use It? Dry or dehydrated skin Sensitive or redness-prone skin Anyone using retinoids or acids who needs comfort and barrier support Who Should Avoid It? Rare stickiness with very thick formulas Ensure HA is sealed with a moisturizer in very dry climates How to Use It in a Routine Apply to slightly damp skin to enhance absorption (PubMed) Seal with a cream or oil to prevent water loss Safe to use AM and PM, compatible with most actives including Vitamin C, Niacinamide, and Retinol Side Effects Generally well-tolerated; very rare irritation Possible slight stickiness if over-applied Verdict Hyaluronic Acid is a gentle, universal hydrator. Works best when applied to damp skin and sealed in with a moisturizer for long-lasting hydration. FAQs Is Hyaluronic Acid safe for sensitive skin?Yes, HA is generally well-tolerated and considered gentle. Patch testing is recommended if your skin is extremely sensitive (DermNet NZ). Can I use HA with retinoids or acids?Yes. HA helps buffer potential irritation from retinoids, AHAs, or BHAs, making your routine more comfortable (PMC). Should I apply HA to dry or damp skin?Apply to slightly damp skin to enhance water-binding properties, then seal with a moisturizer (PubMed). Can HA make skin greasy?HA itself is non-oily. Slight stickiness may occur if layered with heavy creams or oils. How often can I use Hyaluronic Acid?HA is safe for daily use, morning and night, and can be layered with most skincare products (PubMed). Does HA reduce wrinkles?HA mainly hydrates and plumps skin, reducing the appearance of fine lines. Maintaining hydration long-term supports skin resilience (PMC). What is the difference between low- and high-molecular-weight HA?Low-molecular-weight HA penetrates deeper to hydrate and improve elasticity, while high-molecular-weight HA sits on the surface for immediate plumping and barrier support (PubMed). Can I mix HA with Vitamin C or Niacinamide?Yes, HA pairs well with most actives, enhancing comfort without interfering with their effects (DermNet NZ). References Bukhari SNA, et al. "Hyaluronic Acid: A key molecule in skin aging." PubMed, 2009. DermNet NZ – Hyaluronic Acid in Skincare Baumann L. "Cosmeceuticals: Topical Hyaluronic Acid and Skin Hydration." PMC, 2017. Related Guides Retinol Guide – Layering and Benefits Niacinamide – Benefits and Uses Hyaluronic Acid vs Glycerin – Which Hydrator Works Better? 👉 Looking for a beginner-friendly hydrator? Try our Hyaluronic Serum for Clear Skin, formulated with multi-weight hyaluronic acid for immediate and lasting hydration.

Reviewed by Thank Me Now Skincare Editor · Last updated: September 2025 Niacinamide (Vitamin B3) is one of the most researched and versatile skincare ingredients. Known for its ability to calm redness, minimise pores, and support a healthy skin barrier, it's a go-to for all skin types, from sensitive to acne-prone. What is Niacinamide? Niacinamide is a water-soluble form of Vitamin B3 that works with your skin's natural processes to strengthen its barrier, improve hydration, and visibly smooth texture. It is non-acidic and typically well-tolerated, even at higher concentrations. Key Benefits Reduces appearance of pores by regulating sebum production (PubMed) Brightens dull or uneven tone and fades dark spots (PMC) Soothes redness and strengthens the skin barrier (DermNet NZ) Improves skin elasticity and texture over time Balances oil without over-drying, making it ideal for acne-prone skin Who Should Use It? Oily or combination skin Sensitive or redness-prone skin Acne-prone or breakout-prone skin Mature skin seeking smoother texture and even tone Who Should Avoid It? Those who experience irritation at high concentrations (>10%) People using multiple strong actives simultaneously — reduce frequency to avoid barrier stress How to Use It in a Routine Use AM or PM after cleansing, before moisturiser Pairs well with hyaluronic acid, peptides, ceramides If using with strong acids or retinoids, alternate days or apply in different routines Verdict Niacinamide is one of the safest, most effective daily actives for all skin types — perfect for calming redness, improving texture, and boosting radiance. 👉 Ready to add Niacinamide to your routine? Try our Hydrating Glow Serum — formulated to soothe, hydrate, and restore balance. FAQs Is Niacinamide safe during pregnancy?Yes, topical niacinamide is generally considered safe, but consult your doctor if you have concerns. Can I combine Niacinamide with Retinol or Vitamin C?Yes — dermatologists often recommend pairing them. Use Vitamin C in the morning and Niacinamide morning or evening. Retinol can be used at night with Niacinamide layered before or after. How long until I see results?Most people see noticeable improvement in tone and texture in 4–8 weeks with consistent use. References Draelos ZD. “The Effect of 2% Niacinamide on Facial Sebum Production.” J Cosmet Laser Ther. 2006. Bissett DL et al. “Topical Niacinamide Reduces Hyperpigmentation and Improves Skin Appearance.” Dermatol Surg. 2004. DermNet NZ: Niacinamide Overview About the Author: This article is reviewed by the Thank Me Now Skincare Editorial Team, who specialise in ingredient science and routine optimisation. All guides are updated regularly with the latest research. Related Guides How to Layer Niacinamide and Retinol (Without Irritation) Niacinamide vs Azelaic Acid – Redness & Tone Niacinamide vs Vitamin C – Can You Use Them Together?