Niacinamide (Vitamin B3) – Benefits, Side Effects & Uses
Niacinamide (Vitamin B3) is one of the most researched and versatile skincare ingredients. Known for its ability to calm redness, minimize pores, and support a healthy skin barrier, it's a go-to for all skin types, from sensitive to acne-prone.
What is Niacinamide?
Niacinamide is a water-soluble form of Vitamin B3 that works with your skin's natural processes to strengthen its barrier, improve hydration, and visibly smooth texture. It is non-acidic and typically well-tolerated, even at higher concentrations.
Key Benefits
- Reduces appearance of pores by regulating sebum production (PubMed)
- Brightens dull or uneven tone and fades dark spots (PMC)
- Soothes redness and strengthens the skin barrier
- Improves skin elasticity and texture over time
- Balances oil without over-drying, making it ideal for acne-prone skin
Who Should Use It?
- Oily or combination skin
- Sensitive or redness-prone skin
- Acne-prone or breakout-prone skin
- Mature skin seeking smoother texture and even tone
Who Should Avoid It?
- Those who experience irritation at high concentrations (>10%)
- People using multiple strong actives simultaneously — reduce frequency to avoid barrier stress
How to Use It in a Routine
- Use AM or PM after cleansing, before moisturizer
- Pairs well with hyaluronic acid, peptides, ceramides
- If using with strong acids or retinoids, alternate days or apply in different routines
Verdict
Niacinamide is one of the safest, most effective daily actives for all skin types — perfect for calming redness, improving texture, and boosting radiance.
FAQs
Is Niacinamide safe during pregnancy?
Yes, topical niacinamide is generally considered safe, but consult your doctor if you have concerns.
Can I combine Niacinamide with Retinol or Vitamin C?
Yes — dermatologists often recommend pairing them. Use Vitamin C in the morning and Niacinamide morning or evening. Retinol can be used at night with Niacinamide layered before or after.
How long until I see results?
Most people see noticeable improvement in tone and texture in 4–8 weeks with consistent use.
References
- Draelos ZD. “The Effect of 2% Niacinamide on Facial Sebum Production.” J Cosmet Laser Ther. 2006.
- Bissett DL et al. “Topical Niacinamide Reduces Hyperpigmentation and Improves Skin Appearance.” Dermatol Surg. 2004.