Introduction
Niacinamide and Vitamin C are two powerhouse actives often used in modern skincare. While older research once suggested they couldn’t be combined, new studies and advanced formulations show they can work beautifully together when used correctly.
Niacinamide
Reduces redness and regulates oil production (PubMed)
Strengthens the skin barrier, improving resilience (DermNet NZ)
Brightens uneven tone and reduces the look of dark spots
Vitamin C
Potent antioxidant that fights free radical damage (PubMed)
Supports collagen production for firmer-looking skin
Brightens dullness and improves overall skin radiance
Combination
Modern skincare science confirms that Niacinamide and Vitamin C can be layered safely. Many dermatologists recommend using Vitamin C in the morning to protect against environmental damage, and Niacinamide either morning or evening for its calming and oil-balancing benefits. If you prefer simplicity, look for a well-formulated serum that combines both in a single step.
Real-World Insight
We’ve seen incredible results from customers using this combination. Many report fewer breakouts, reduced redness, and a noticeable glow when using Niacinamide and Vitamin C consistently. The key is consistency and using formulas designed to be gentle on all skin types.
Related
See also: Niacinamide Guide, Vitamin C Guide
Related Ingredients
Niacinamide – How it calms redness and strengthens your skin barrier
Vitamin C – The brightening antioxidant every skin routine needs
Niacinamide (Vitamin B3) – Learn about its multi-tasking benefits
References
Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. “Niacinamide: A vitamin that improves aging facial skin appearance.” Int J Cosmet Sci. 2005. PMID: 16029679.
Mechanistic Insights into the Multiple Functions of Niacinamide. PMC, 2023. (Review of latest data on niacinamide’s anti-inflammatory, antimicrobial, barrier-supporting actions)
Pullar JM, Carr AC, Vissers MCM. “The Roles of Vitamin C in Skin Health.” PMC Article. 2017. PMID: 28805671.
A review of topical vitamin C derivatives and their efficacy. Pandey A, Jatana GK, Sonthalia S, et al. 2021. PMID: 34559950.
Bissett DL, Miyamoto K, Sun P, Li J, Berge CA. “Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin.” 2004. PMID: 18492135.
